Back

Patients Multiple sclerosis

Ocrelizumab (Ocrevus): What are the side effects?

202 views
2 times supported
12 comments

Touhaifloash299

06/21/2021 at 2:57 PM

Touhaifloash299

Last activity on 02/21/2022 at 4:51 PM

Joined in 2021

9 comments posted | 9 in the Multiple sclerosis Forum

Rewards

Messenger
Explorer

View profileView Add a friendAdd Write

Hi,

my doctor just put me on ocrelizumab infusions. does anyone know anything about the possible side effects? i'm supposed to have my first one next week so i'm trying to prepare.

thanks fot your answers

All comments

Go to the last comment

Courtney_J

Community manager

06/21/2021 at 6:04 PM

Good advisor

Courtney_J

Community manager

Last activity on 08/08/2022 at 11:09 AM

Joined in 2020

1,334 comments posted | 95 in the Multiple sclerosis Forum

6 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Messenger
Explorer
Friend

View profileView Add a friendAdd Write

Hello johan89, thank you for opening this discussion. Let me tag some other members who can possibly share with you.

Hi everyone, for those of you who have been on or are currently on Ocrevus (ocrelizumab), can you share a bit about side effects? Did you experience any? How long did it take for them to go away? Has it helped your MS?
@Pleyceapreeclou554‍ @Vaystihis512‍ @Hidden username‍ @394Jothahir‍ @Flashasail‍ @Trailhead6392‍ @Reyleesh99‍ @Hidden username‍ @Hidden username‍ @Hidden username‍ @83Plaijeet‍ @7Noohaifleecleck‍ @Clubecloash26‍ @Hidden username‍ @Hidden username‍ @Breeleck97‍ @Brayshaimoack86‍ @Yosteelays85‍

Thanks for sharing with us, your experiences and support are so important!

Take care,
Courtney

See the signature

Courtney_J, Community Manager, Carenity US

Ocrelizumab (Ocrevus): What are the side effects? https://www.carenity.us/forum/multiple-sclerosis/your-opinion-on-multiple-sclerosis-treatments/ocrelizumab-ocrevus-what-are-the-side-effects-3473 2021-06-21 18:04:41

83Plaijeet

Ambassador

06/21/2021 at 6:11 PM

Good advisor

83Plaijeet

Ambassador

Last activity on 10/23/2026 at 12:45 AM

Joined in 2020

100 comments posted | 26 in the Multiple sclerosis Forum

6 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer
Evaluator
Friend

View profileView Add a friendAdd Write

I have been on Ocrevus since 4 months after it received FDA approval for treatment. The first dose (1/2 dose) I had an allergic reaction that caused swelling in my throat. The nurse administered an antihistamine and had me have a quart of water, observed me for 30 minutes and continued the infusion. l highly recommend the medication, and have not had any reactions after the initial 1/2 dose.

See the signature

Dan Varady

Reyleesh99

06/21/2021 at 7:49 PM

Good advisor

Reyleesh99

Last activity on 06/22/2025 at 8:31 PM

Joined in 2020

61 comments posted | 22 in the Multiple sclerosis Forum

4 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer
Evaluator
Friend

View profileView Add a friendAdd Write

I have been taking Ocrevus for about 16 months. I have no complaints with this medication.

Pleyceapreeclou554

07/03/2021 at 9:30 PM

Good advisor

Pleyceapreeclou554

Last activity on 09/13/2025 at 10:39 PM

Joined in 2020

60 comments posted | 21 in the Multiple sclerosis Forum

4 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer
Friend

View profileView Add a friendAdd Write

My neurologist decided to take me off of the Okrevus due to some abnormalities in my lab work. And she mentioned my age could be an issue. For goodness sake I'm only 56. I did experience One flare in the past 3 weeks got my Solu-medrol treatments 1 Gm/ day X3 days.

See the signature

Melissa Vemi

Ceecrail5

08/31/2021 at 2:00 AM

Ceecrail5

Last activity on 06/12/2025 at 5:58 AM

Joined in 2020

4 comments posted | 3 in the Multiple sclerosis Forum

Rewards

Explorer
Newsfeeder

View profileView Add a friendAdd Write

I have been on ocrevus for 5 years, I look forward to the infusions as I have a group of people that I get to visit with. We all schedule our infusions on the same day to catch up and have some fun. Join us at Dr. Gitt's office, he is a great neurologist and has managed to keep me free from any flare ups. Going in for an infusion once every 6 months is so much better than the injections I was taking, breaking my skin down.

I have not had any problems at all with the infusion, one of the gals says she gets a headache afterwards and it goes away.

I love it!!!!

Woplee284

04/15/2023 at 12:42 PM

Good advisor

Woplee284

Last activity on 04/21/2024 at 8:17 PM

Joined in 2022

603 comments posted | 35 in the Multiple sclerosis Forum

24 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Messenger
Explorer
Friend

View profileView Add a friendAdd Write

Hi @Touhaifloash299 @83Plaijeet @Reyleesh99 @Pleyceapreeclou554 @Ceecrail5

How are you guys doing today?

I want to encourage everyone to post their treatment reviews here https://member.carenity.us/medications

This new feature is where Carenity members can leave their opinions about side effects and medicine efficacy.

Take care,

Lizzi from the Carenity team

See the signature

LizziB

Foleesheyr46

05/07/2023 at 10:02 PM

Foleesheyr46

Last activity on 09/11/2024 at 11:39 PM

Joined in 2020

1 comment posted | 1 in the Multiple sclerosis Forum

Rewards

Explorer

View profileView Add a friendAdd Write

I did 2 infusions, made me worse also ended up with breast cancer!

Close all

See the responses

Woatreho90

Edited on 04/23/2024 at 3:55 AM

Woatreho90

Last activity on 04/21/2024 at 9:57 AM

Joined in 2024

2 comments posted | 2 in the Multiple sclerosis Forum

1 of their responses was helpful to members

Rewards

Explorer

View profileView Add a friendAdd Write

@Foleesheyr46 Sending you prayers, I was diagnosed in 2010 and seemed to go down hill quickly. In six years I could no longer work and had real problems with balance and joint pain. Brain fog was really bad sometimes. I took rebif and had a lot of problems and had to quit. I have been on techfadera (not spelled right) for a few years and have several side effects. I felt lost and decided to quit my meds due to side effects. Our care provider introduced me to Ayurvedic treatment. I had a total decline of all symptoms including vision problems, numbness and others. Sometimes, i totally forget i ever had MS. [This content has been moderated by an administrator] I am very pleased with this treatment. I eat well, sleep well and exercise regularly. God bless all MS Warriors

Hide the responses

83Plaijeet

Ambassador

04/19/2024 at 5:04 PM

Good advisor

83Plaijeet

Ambassador

Last activity on 10/23/2026 at 12:45 AM

Joined in 2020

100 comments posted | 26 in the Multiple sclerosis Forum

6 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer
Evaluator
Friend

View profileView Add a friendAdd Write

The only side affect I had was because they did not administer the Benadryl in the correct order. You will be fine. I was one of the first in my state to get it and it is a game changer.

See the signature

Dan Varady

Pleyceapreeclou554

04/20/2024 at 10:26 PM

Good advisor

Pleyceapreeclou554

Last activity on 09/13/2025 at 10:39 PM

Joined in 2020

60 comments posted | 21 in the Multiple sclerosis Forum

4 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer
Friend

View profileView Add a friendAdd Write

I was on ocrelizumab for a number of years and then I ended up with leukopenia and they took me off of it so I'm not on any disease modifying drugs. It was good when I was on it until it wasn't good for me all depending on your body. Good luck with your journey.

See the signature

Melissa Vemi

Reedreeng7975

Edited on 02/10/2026 at 11:50 AM

Reedreeng7975

Last activity on 05/09/2026 at 7:06 AM

Joined in 2025

Family/friend of a patient with Lung cancer since 2025

1 comment posted | 1 in the Multiple sclerosis Forum

1 of their responses was helpful to members

Rewards

Explorer

View profileView Add a friendAdd Write

i once was on this meds and i started feelings different. went to see my doctor about it turns out the side effects were because i continued taking my [This content has been moderated by an administrator] which i had to stop. hope you get well soon but you gotta quit all other things

Members are also commenting on...

Articles to discover...

08/03/2026 | News

When summer gets tough: Understanding the link between heat and multiple sclerosis

05/30/2026 | News

MS: When the bladder malfunctions - A symptom that isn't discussed enough

01/23/2026 | Advice

Talking about MS: Here's what to share and what to keep private in real-life conversations

09/17/2025 | Testimonial

MS: “It's deeply linked to stress, so it's important to take care of your emotions.”

02/01/2019 | Advice

Brain fog: Causes and how to cope

11/26/2018 | Testimonial

Multiple Sclerosis And The Success And Side-Effects With Various Treatments

08/17/2018 | Testimonial

No One Knows What Being Diagnosed with Multiple Sclerosis Is Like, So Maintain A Can-Do Attitude

01/15/2020 | Testimonial

MS, prickling sensations, treatments: my battle to walk again

Ocrelizumab (Ocrevus): What are the side effects?

All comments

Give your opinion

Members are also commenting on...

Articles to discover...

Medication fact sheets - patient opinions...