What do you do when the medications you take for depression stop working?

i took a previous medication that caused me to gain weight, so I switched it to Lexapro which has been working so far

Hi everyone. @LizziB, thx for question. Meds can stop working anytime, for any reason. My first line of thought is talk w doc about why they've stopped working, try to stagger dosages, up or down. Look into therapy, of any type. I believed 1 or more of my meds stopped working, but the psych changed my mind, effectively. So, no med changes lately. A neighbor I know, has horrible time on meds, they keep them up, they have more symptoms than previously. Their psych, I don't quite understand it, but won't alter his meds. He's as sleep deprived as me, minus the apnea. Poor guy.

What have u others found helps?

I've been on Welbutrin for a number of years. I felt that I might be due for a change, so I passed it by my primary physician. She put me on Vraylar along with Welbutrin. I was surprised how well that worked. No more anxiety episodes! Not bad for a tiny 2 mg pill. Next we addressed the letter I received from my insurance company. They told my I'd aged out of Welbutrin. Since it was working, the NP-C said to stay on it and use the Good RX card to my local food store and the 90 day supply, twice per day cost was less than $2 difference. I'm 73 yrs old so not quite ready to roll over and play dead. Hang tough my fellow MS friends! Don't allow insurance push you around!